Novel Chimeric Protein Vaccines Against Clostridium difficile Infection
نویسندگان
چکیده
منابع مشابه
Clostridium difficile Infection.
Clostridium difficile infection is a major health care challenge in terms of patient and economic consequences. For the patient, it is a morbid and sometimes a life-threatening iatrogenic complication of antibiotic treatment. In the United States, the provider's institution may face financial penalties, because the Centers for Disease Control and Prevention views this as an iatrogenic health ca...
متن کاملClostridium difficile infection
Autopsy and Case Reports. ISSN 2236-1960. Copyright © 2014. This is an Open Access article distributed of terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted noncommercial use, distribution, and reproduction in any medium provided article is properly cited. Clostridium difficile infection (CDI) is a significant and increasing medical problem, surpassing m...
متن کاملClostridium difficile infection.
Clostridium difficile infection is associated with broad-spectrum antibiotic therapy and is the most common cause of infectious diarrhea in hospital patients. Pathogenic strains of C. difficile produce two protein exotoxins, toxin A and toxin B, which cause colonic mucosal injury and inflammation. Infection may be asymptomatic, cause mild diarrhea, or result in severe pseudomembranous colitis. ...
متن کاملDoes doxycycline protect against development of Clostridium difficile infection?
BACKGROUND Receipt of antibiotics is a major risk factor for Clostridium difficile infection (CDI). Doxycycline has been associated with a lower risk for CDI than other antibiotics. We investigated whether doxycycline protected against development of CDI in hospitalized patients receiving ceftriaxone, a high-risk antibiotic for CDI. METHODS We studied adults admitted to an academic county hos...
متن کاملDoes Candida species overgrowth protect against Clostridium difficile infection?
TO THE EDITOR—We read with interest the article by Nerandzic et al [1] reporting the prevalence and acquisition of Candida species in stool of patients treated for Clostridium difficile infection (CDI). Although not specifically addressed in the article, the isolation of Candida spp from the stool of only 16% of pretreated patients is intriguing, given the high prevalence of Candida spp in the ...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2018
ISSN: 1664-3224
DOI: 10.3389/fimmu.2018.02440